Omega-3 Relieves Depression in Some Individuals
Omega-3 oils contain fatty acids that are known as essential
fatty acids because they cannot be manufactured in your body but
have to be taken in your diet. They provide many benefits to your
body, and are also believed to relieve depression in some
individuals. First, however, an overview of the more conventional
benefits of omega-3 oils.
Obtainable in your diet from oily fish such as mackerel, herring,
salmon and the like, omega-3 fatty acids play an important part in
your normal growth and development, and are also crucial to normal
brain function. They can reduce inflammation and protect you from
heart disease and some cancers. Studies have shown the fatty acids
to be particularly concentrated in the brain and to be important
for cognitive processes and memory.
The effects of omega 3 fish oils on the brain are well documented,
and they are known to be effective treatments in some cases of
bipolar and schizophrenia. It is believed that they could also be
used as a treatment in other disorders such as attention deficit
disorder and dyslexia, but there is as yet no evidence that this is
the case.
Omega-3 fatty acids reduce the so-called ‘bad’ low density
lipoprotein (LDL) cholesterol levels and increase the high density
lipoproteins (HDL) that take the cholesterol back to the liver for
destruction. The end result is a reduction in the cholesterol
content of the blood that can be deposited on the artery walls and
promote atherosclerosis. Diets high in omega-3 fatty acids appear
to lower blood pressure in those suffering from hypertension, and
so reduce their chances of heart attacks and strokes.
Omega 3 oils are also natural inflammatories, and help prevent
conditions involving inflammation such as arthritis, asthma and
menstrual cramps. They appear to help the immune system to fight
these conditions and reduce the inflammation and its causes.
They are also important in the formation of prostaglandins that are
responsible for the regulation of important functions such as blood
pressure, blood clotting and immune response. They are hormone-like
substances and also control the synthesis in the body of other
hormones. If the balance of fatty acids in the diet is not right,
then the subsequent imbalance in prostaglandin and hormone
production can lead to disease.
It is in its effect on depression and mood, however, that has
surprised many in the medical, profession. Ethyl-eicosapentaenoate,
known as ethyl EPA, is a constituent of omega-3 fish oil and many
studies have demonstrated that this substance helps cases of
depression and related disorders. However, are people justified in
turning to ethyl EPA to help them be cured of this condition?
In one study involving 20 people, six out of ten people given
the supplement displayed significantly reduced symptoms of
depression after four weeks. The effects were noticed as early as
two weeks and many of the depression symptoms, such as
worthlessness and insomnia, had improved after three weeks. This
conformed with the results of many other studies that have been
carried out world wide. In Scotland, a number of patients were
studied who had failed to respond to traditional antidepressant
drugs. Of the seventy patients involved in the trial, all of the
patients who were treated with EPA displayed significant
improvements in all the symptoms of their depression after four
weeks whereas those with the placebo showed no improvement.
Of the two main components of omega-3 fish oil, EPA and
docosahexaenoic acid (DHA), only the EPA has this property, and the
EPA works best alone when the DHA has been extracted. Studies and
tests have indicated that the DHA appears to be important for the
brain’s structure, but the EPA for its function, hence the reason
for the ineffectiveness of the former in relieving depression which
is a function of the brain rather connected to its structure. In
fact, depressed people have been found to be deficient in EPA in
comparison to those not suffering from the condition.
The original idea for this originated with the late Dr. Horribin
who was pioneer in researching the effects of lipids on the
biochemistry of the brain as far back as the 1970s. Since then the
world-wide research has confirmed his theory. However, the reason
why this theory works in practice is not yet understood. It has
been established that a diet rich in trans fats can unfavorably
affect the hormones in the brain that stabilize mood, possibly due
to the fats slowing down the system of messaging within the brain.
This kind of effect can cause depression.
This is likely due to the slowing down of the messages passing
between the synapses. Brain cells communicate by means of chemicals
that cross the synapses, or small gaps between the individual
cells. They are not directly connected like normal electrical
circuits. It has been theorized that the EPA speeds up the passage
of these messages between neurotransmitters and neuroreceptors.
Other theories have also been promoted, such as that the EPA has
properties of its own that cure depression by another route
altogether.
A possible clue could be in the findings of one study on a man aged
21 years old whose brain was scanned before and after EPA
treatment. The result showed in increase in the mass of brain cells
after the treatment. This was contrary to the belief that brain
cells could neither be generated nor grown once a person reaches
maturity.
An individual suffering depression who would like to treat
themselves with EPA would have to buy a lot of oily fish since high
doses are needed for this level of therapy. However, it is found in
high concentrations in a few supplements available on the market,
and when choosing you must use the highest grade of EPA you can
get, with as low a DHA content as you can find.
There is little doubt now; however, that the EPA content of omega-3
relieves depression in some individuals, although more work is
needed to prove without doubt that it is effective with all forms
of depression.
About the Author
More information on Omega-3 Fish Oil is available at VitaNet,
LLC Health Food Store. http://vitanetonline.com/
Alternative Health Articles Site
|